Heat a large skillet over medium heat and add the ground beef. Cook for 5–7 minutes, breaking it apart until completely browned.

Once the beef is browned, add chili powder, cumin, garlic powder, onion powder, salt, and pepper. Stir well and cook for an additional 2–3 minutes.

Remove the skillet from heat and sprinkle cheddar cheese over the beef mixture. Stir gently until the cheese melts completely.

In a non-stick skillet, place a flour tortilla on medium heat. Add a quarter of the beef and cheese mixture and an extra 1/4 cup of shredded cheese on one half of the tortilla, fold it over.

Cook the folded quesadilla for 2–3 minutes on each side until golden brown and crispy.

Slice the quesadillas into wedges and serve warm with your favorite toppings.